The Problem with NMDA is its extremely high cost to manufacture the raw material. It is about 20 times more expensive than ordinary D-Aspartic Acid. However, much less is needed to provide an ethical dosage for testosterone elevation. APS uses an ultra- pure,99.9% Pharmaceutical-Grade N-Methyl-D-Aspartic Acid for NMDA receptor activation and allosteric modulation. Activation of the NMDA receptor has shown a direct relation to increases in Luteinizing Hormone (LH) and Testosterone . Several studies have shown the relation between LH, Testosterone, NMDA activation, and NMDA administration.
99.9% Pharmaceutical-Grade N-Methyl-D-Aspartic Acid
NMDA has been proven to be 100x stronger than D-Aspartic Acid! Until now, the only way to activate the NMDA receptors is by using a relatively weak NMDA receptor activator, D-Aspartic Acid. D-Aspartic Acid quickly became popular when people studies revealed it could raise their testosterone by 42% in as little as 12 days. While that may sound remarkable, it has been clinically proven that while D-Aspartic Acid can activate the NMDA receptor, pure NMDA can activate the NMDA receptor more than 100x (10,000%) more effectively! So you may ask why do most supplement companies only offer the weaker version- D-Aspartic Acid (DAA). Pharmaceutical-grade NMDA costs over 20 times more than DAA but is 100 times more potent! NMDA 100 contains an incredible 100mg of pure NMDA that will be delivered straight to NMDA receptors that can then lead to unimaginable hormonal elevation! Other products claiming to contain NMDA, but very few contain 99.9% pure NMDA, and none of them deliver 100mg of this potent compound!
Background: Aspartic acid is one of the 20 common amino acids that are used by the body to construct proteins and is considered to be non-essential since it can be made from oxaloacetate, an intermediate of the tricarboxylic acid cycle. There are two isomers of aspartic acid, the L-isomer and the D-isomer. Only the L-isomer is used in proteins while the d-isomer is used as a neurotransmitter as D-Aspartic acid and N-methyl-D-aspartic acid. D-aspartic acid is known to stimulate the NMDA receptor.
More recently, D-aspartic acid has been shown to have some intriguing effects in several animal species and humans. D-aspartic acid has been shown to enhance gonadotropin, releasing hormone from the hypothalamus as well as growth hormone (GH) and luteinizing hormone (LH) release from the pituitary. Sodium D-aspartic acid has also been shown to directly increase testosterone production by the testes , DAA does this by increasing the levels of steroidogenic acute regulatory (StAR) protein. StAR plays a critical role in the production of steroid hormones in the testes and adrenals. In fact, StAR
mediates the rate-limiting step in steroid hormone production, the importation of cholesterol into the mitochondria. All steroid hormones are manufactured from cholesterol in the mitochondria and if cholesterol doesn’t get into the mitochondria, then steroid hormones, and more specifically, testosterone does not get produced. DAA increases StAR which increases cholesterol entry into the mitochondria which results in increased testosterone production.
A study dosed 3.12 grams of sodium-DAA to adult males (27 to 37 yrs old) for 12 days resulting in a 42% increase in average testosterone levels. These may not seem like huge increases in testosterone but these are controlled, scientific results in normal healthy men . DAA is an natural amino acid that has been shown to raise testosterone levels in men, but, unfortunately, straight DAA has terrible water solubility (less than 1 gram will dissolve in 220 milliliters of water). This means that it basically sits in the digestive tract as a gritty powder and absorbs very slowly.
APS was the first company to introduce D-Aspartic/NMDA technology to the market back in 2008. In fact, our groundbreaking discoveries with the product NMDA launched an entirely new category in the sports nutrition market! In fact, we found the Italian patent that invalidated Ron Kramer’s bogus patent on DAA. However, NMDA’s formula is still light years ahead of our competition and we guarantee that NMDA 100 is absolutely the most powerful and effective natural, non-steroidal testosterone increaser on the market
Advanced Delivery System Provides Better Absorption
APS NMDA 100 utilizes an exclusive, proprietary and novel delivery system that combines complimentary properties of liposomes and polymeric nanoparticles i.e. nanolipobeads represent a new trend in the application of site specific target compound delivery. The problem with hormone most products on the market is that are not bio-available and do not allow you to see the amazing benefits of testosterone.
APS uses a unique preparation of nanolipobeads involves three important steps- (a) Preparation of PVA hydrogel nanopartices by emulsification followed by freeze thaw cyclization method (b) Surface acylation of PVA nanoparticles by treatment with polmityl chloride and (c) Preparation of nanolipobeads by formation of PE liposome on acylated PVA hydrogel nanoparticles by vesicles fusion. The Preparation of PVA hydrogel nanopartices was then optimized by various formulation and process variables variables e.g. polymer concentrations, drug concentration, emulsifier concentrations, and a number of freeze thaw cycles, stirring speed, stirring time, and sonication time to obtain nanosized PVA hydrogel nanoparticles with maximum entrapment efficiency. This scientifically-engineered delivery system allows APSNMDA 100 to be delivered into the blood stream more rapidly, where they can be better absorbed and utilized without degradation in the liver as is experienced with other products. APS holds the worldwide rights to this unique product and advanced technology protein/peptide delivery system to this incredible Testosterone and [GnRH] Gonadotropin-Releasing Hormone Trigger.